7,502 research outputs found
Few-electron quantum dots in III-V ternary alloys: role of fluctuations
We study experimentally the electron transport properties of gated quantum
dots formed in InGaAs/InP and InAsP/InP quantum well structures grown by
chemical-beam epitaxy. For the case of the InGaAs quantum well, quantum dots
form directly underneath narrow gate electrodes due to potential fluctuations.
We measure the Coulomb-blockade diamonds in the few-electron regime of a single
quantum dot and observe photon-assisted tunneling peaks under microwave
irradiation. A singlet-triplet transition at high magnetic field and
Coulomb-blockade effects in the quantum Hall regime are also observed. For the
InAsP quantum well, an incidental triple quantum dot forms also due to
potential fluctuations within a single dot layout. Tunable quadruple points are
observed via transport measurements.Comment: 3.3 pages, 3 figures. Added two new subfigures, new references, and
improved the tex
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Uric Acid as a Potential Peripheral Biomarker for Disease Features in Huntington's Patients.
Oxidative stress has long been implicated in the pathophysiology and progression of Huntington's disease (HD). Uric acid (UA) is a naturally occurring antioxidant that is present in the brain and periphery. Growing evidence has implicated UA as a molecular biomarker for several neurodegenerative diseases, most notably Parkinson's disease (PD). In this study, we investigated UA levels in clinical samples from HD patients and normal controls (NCs) and assessed potential relationships between UA levels and disease and clinical data. UA levels were measured in plasma (n = 107) and saliva (n = 178) samples from premanifest (pre-HD) and manifest HD patients and control subjects. Gender effects of UA levels were observed in both biofluids, with male patients showing higher UA levels compared to female patients. Comparisons of UA levels across diagnostic groups, separated by gender, revealed that both plasma and salivary UA levels were significantly lower in female pre-HD and manifest HD patients compared to NCs. Salivary levels of UA were also significantly lower in male manifest HD patients versus controls, but not in plasma. Correlations of peripheral UA levels to clinical data also showed differences according to gender. In male HD patients, both plasma and salivary UA levels were significantly negatively correlated with total functional capacity (TFC), while positive correlations were observed with total motor score (TMS). Female HD patients showed a significant positive correlation between plasma UA levels and TMS, while salivary UA levels from female patients were significantly correlated to disease burden. Finally, in a separate cohort, we show that UA levels are decreased in postmortem prefrontal cortical samples (n = 20) from HD subjects compared to matched controls. These findings suggest that decreased levels of UA in the brains of HD patients can be reflected in peripheral fluids, with salivary measures of UA particularly offering significant promise as a potentially relevant, non-invasive biomarker of disease symptoms and burden. Our findings further highlight the impact of sexual dimorphism in HD pathophysiology
A Tuneable Few Electron Triple Quantum Dot
In this paper we report on a tuneable few electron lateral triple quantum dot
design. The quantum dot potentials are arranged in series. The device is aimed
at studies of triple quantum dot properties where knowing the exact number of
electrons is important as well as quantum information applications involving
electron spin qubits. We demonstrate tuning strategies for achieving required
resonant conditions such as quadruple points where all three quantum dots are
on resonance. We find that in such a device resonant conditions at specific
configurations are accompanied by novel charge transfer behaviour.Comment: 11 pages, 4 figure
Reducing the Bias of Causality Measures
Measures of the direction and strength of the interdependence between two
time series are evaluated and modified in order to reduce the bias in the
estimation of the measures, so that they give zero values when there is no
causal effect. For this, point shuffling is employed as used in the frame of
surrogate data. This correction is not specific to a particular measure and it
is implemented here on measures based on state space reconstruction and
information measures. The performance of the causality measures and their
modifications is evaluated on simulated uncoupled and coupled dynamical systems
and for different settings of embedding dimension, time series length and noise
level. The corrected measures, and particularly the suggested corrected
transfer entropy, turn out to stabilize at the zero level in the absence of
causal effect and detect correctly the direction of information flow when it is
present. The measures are also evaluated on electroencephalograms (EEG) for the
detection of the information flow in the brain of an epileptic patient. The
performance of the measures on EEG is interpreted, in view of the results from
the simulation study.Comment: 30 pages, 12 figures, accepted to Physical Review
The visibility study of S-T Landau-Zener-St\"uckelberg oscillations without applied initialization
Probabilities deduced from quantum information studies are usually based on
averaging many identical experiments separated by an initialization step. Such
initialization steps become experimentally more challenging to implement as the
complexity of quantum circuits increases. To better understand the consequences
of imperfect initialization on the deduced probabilities, we study the effect
of not initializing the system between measurements. For this we utilize
Landau-Zener-St\"uckelberg oscillations in a double quantum dot circuit.
Experimental results are successfully compared to theoretical simulations.Comment: 8 pages, 5 figure
Influence of surface tension, osmotic pressure and pores morphology on the densification of ice-templated ceramics
International audienceWe attempt here to clarify the influence of the nature of the solvent on the ice-templating process, based on literature experimental results of porosity and suspension concentration. In particular, we compare the relative influence of surface tension, osmotic pressure and the pore size and radius of curvature on the densification of the green bodies. Variations of the osmotic pressure when changing the solvent can yield significantly different behaviour during the freezing stage and therefore significantly affect the densification behaviour, an effect not apparent when using the Shanti model. In addition, and equally important, a modification of the macropores morphology is induced by the evolution of the solvent crystals morphology, and resulting in smaller and more intricate crystals and macropores which facilitates the densification. The radius of curvature is probably also an essential parameter controlling the densification of ice-templated ceramics
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